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KMID : 0644120190320010085
Journal of Oriental Gynecology
2019 Volume.32 No. 1 p.85 ~ p.93
Treatment of Mid-trimester Oligohydramnios Using Gami-danggui-sa
Kim Hyo-Jung

Kim Eun-Seop
Jin Dae-hwan
Hwang Deok-Sang
Lee Jin-Moo
Lee Chang-Hoon
Jang Jun-Bock
Abstract
Objectives: The aim of this study was to demonstrate the benefit of Traditional Korean Medicine as an adjuvant therapy in management of mid-trimester oligohydramnios.

Methods: It is a case report of a 31 year-old woman hospitalized for oligohydramnios at 24+4/7weeks of gestation. This patient diagnosed with special oligohydramnios had no abnormal findings such as fetal urinary abnormalities or other anomalies. Also, symptom of PPROM (preterm premature rupture of membrane) was not confirmed. The decoction, Gami-danggui-san (DG) was prescribed for the purpose of reducing unnecessary contraction of uterine muscle during pregnancy and promoting blood circulation and metabolism, thereby improving placental function and contributing to the increase of the fluid. DG decoction was administered twice a day until 19th of June, which was 10 days in total. During the treatment, level of amniotic fluid had been monitored by measuring AFI (amnioti fluid index).

Results: After these conventional therapies, the amount of amniotic fluid increased steadily, and eventually reached the optimal level. AFI was found to be 3.2 on the 24+4/7 weeks, 8 on the 26+1/7 weeks, 11.5 on the 27+0/7 weeks of gestation. In the same periods, EFW (expected fetal weight) was also found to be increasing gradually: 545 g, 630, and 760 g.

Conclusions: Our report implies the potential of herbal medicine as a effective therapy for oligohydramnios tratment. Further studies are needed to assess the efficacy of TKM herbal medicine and reveal the mechanisms of the decoction.
KEYWORD
Oligohydramnios, Gami-danggui-san, Amniotic Fluid Index, Korean Traditional Medicine
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